One challenging thing for a DM to handle is what happens when a player doesn’t manage to come to a session for whatever reason? Or more precisely, what happens to that players character for the session? Do they go poof in a puff of smoke like some kind of Houdini, to reappear suddenly the next session the player returns? Do you give them special DM plot armor? Are they controlled by another player instead? There are many questions to be answered and various solutions you can use to get through what a character does when their player is absent. The most important thing to bear in mind that as the DM, it’s ultimately your decision what happens to a players character and trust between you (the DM) and your players is paramount.
Just as a warning, the first part of this post and why I’ve decided to write it was prompted by a player having their character sexually assaulted, raped and left pregnant by the attack by their DM. After that I will be describing things in general terms and without any further sexual assault or similar connotations (as it will be largely my own experiences at that point and honestly, I can’t say I’ve ever wanted to do that to a character *ever*).